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Fig. 6 | Genes and Environment

Fig. 6

From: Construction of reporter gene assays using CWP and PDR mutant yeasts for enhanced detection of various sex steroids

Fig. 6

Responses of reporter gene assay yeast strains expressing PR (W303a, cwp1Δpdr5Δ, and cwp1Δcwp2Δ) and AR (W303a, cwp1Δpdr5Δ, and pdr5Δpdr10Δ) to known antagonist ligands. PR assay yeasts were exposed to Mif (A and B) and Spi (C and D), and AR assay yeasts were exposed to Flu (E and F) and Zer (G and H). Antagonistic activity (A, C, E, and G) and partial agonist activity (B, D, F, and H) were measured. CYC yeasts (W303a, cwp1Δpdr5Δ, cwp1Δcwp2Δ, and pdr5Δpdr10Δ) were used as references in antagonist assays. Data represent the mean ± SD of triplicate experiments

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Genes and Environment

ISSN: 1880-7062

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