Fig. 11
From: Metabolism and biomarkers of heterocyclic aromatic amines in humans
Co-oxidation of HbO2 by N-hydroxylated aromatic amines and HAAs in human RBCs and met-Hb formation. The mass spectrum of the AαC sulfinamide formed at the β-Cys93 of Hb was acquired by ion trap mass spectrometry employing electrospray ionization in the positive ion mode. The AαC-modified Hb was digested with Glu-C, and the peptide sequence encompassing the AαC sulfinamide adduct formed at Hb β-Cys93 is reported. Adapted with permission from [226]