Fig. 1
From: 1,3-Butadiene: a ubiquitous environmental mutagen and its associations with diseases
The metabolic pathways of BD. The P450-mediated metabolism is an established pathway and the MPO-mediated one is a proposed pathway. (P450s, cytochrome P450 enzymes; ADH, alcohol dehydrogenase; MPO, myeloperoxidase; GSH, glutathione)