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Fig. 4 | Genes and Environment

Fig. 4

From: LncRNA PVT1 induces apoptosis and inflammatory response of bronchial epithelial cells by regulating miR-30b-5p/BCL2L11 axis in COPD

Fig. 4

Overexpressing BCL2L11 abates sh-PVT1-mediated effects on 16HBE cell apoptosis and inflammation under CSE treatment. A-B RT-qPCR and western blotting for determining BCL2L11 overexpression efficiency. C CCK-8 for evaluating the viability of 16HBE cells with indicated treatments. D, E Flow cytometry for measuring cell apoptosis. F Western blotting for detecting apoptosis-related proteins. G, H ELISA for examining concentrations of IFN-γ and TNF-α. **p<0.01, ***p<0.001 vs. sh-NC group; ##p<0.01 vs. sh-PVT1 + vector group

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Genes and Environment

ISSN: 1880-7062

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