Fig. 5

PVT1 depletion ameliorates COPD in rats. A Representative images of HE staining for histological observation of rat lung tissues of each group. B-D RT-qPCR for determining expression of PVT1 (B), miR-30b-5p (C) and BCL2L11 (D) in rat lung tissues. E Measurement of BALF protein concentration. F, G ELISA for examining concentrations of IFN-γ and TNF-α in the serum of rats. **p < 0.01, ***p < 0.001; ##p < 0.01 vs. COPD + LV-NC group