Table 1 Reported Ames test data
From: Structure-mutagenicity relationships on quinoline and indole analogues in the Ames test
Chemical name | Ames test result | Test strains used | Reference | |
|---|---|---|---|---|
Quinoline analogues | ||||
 Quinoline | Mutagenic (+ S9) in TA100, TA98, WP2uvrA | TA100, TA1535, TA98, TA1537, WP2uvrA (± S9) | [9] | |
 Isoquinoline | Non-mutagenic | TA100, TA98 (± S9) | [10] | |
 Quinoxaline | Mutagenic (+ S9) in TA98 | TA100, TA98, TA102 (± S9) | [7] | |
Non-mutagenic | TA100, TA1535, TA98, TA1537, TA1538a | [7] | ||
 Phthalazine | Non-mutagenic | TA100, TA98 (± S9) | [11] | |
Indole analogues | ||||
 Indole | Mutagenicb | WP2, WP2uvrA/pKM101, WP2uvrA, TA102 (± S9) | [12] | |
Non-mutagenic | TA100 (-S9) | [13] | ||
Non-mutagenic | TA100, TA98 (-S9) | [14] | ||
 Indazole | Non-mutagenic | TA100, TA98 (-S9) | [14] | |
 Benzimidazole | Weakly mutagenic in HisG46 and TA1530 (-S9)c | HisG46, TA1530, TA1531, TA1532, HisD3052, TA1534 (-S9) | [15] | |
Non-mutagenic | TA100, TA98 (-S9) | [14] | ||
Non-mutagenic | TA100, TA1535, TA98, TA1537, TA97 (± S9) | [16] | ||