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Table 3 Results of Ames test and in silico analyses of quinoline analogues

From: Structure-mutagenicity relationships on quinoline and indole analogues in the Ames test

  1. +++: "mutagenic (>1000 revertants/mg)" in Ames test
  2. ++: "mutagenic (100-1000 rev/mg)" in Ames test
  3. +: "mutagenic (< 100 revertants/mg)" in Ames test, "positive" in CASE Ultra and "probable" in Derek Nexus
  4. ±: "inconclusive" in CASE Ultra and "equivocal" in Derek Nexus
  5. -: "non-mutagenic" in Ames test, "negative" in CASE Ultra, "inactive" in Derek Nexus
  6. DEREK version: Derek Nexus: 6.1.1, Nexus: 2.4.0, CASE Ultra Version: 1.8.0.5
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Genes and Environment

ISSN: 1880-7062

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