Table 5 False positive rate of ddE based decision on PAAs with ortho substitution
| Example | False positive ratea |
|---|---|---|
Class 1: two CH2CH3 or larger substituents at both R1 and R2 |
| 88.9% (8/9) |
Class 2: one CH2CH3 or larger substituent at ortho position with and without the other ortho substitution |
| 55.0% (44/80) |
Class 3: Smaller substituents at R1 and/or R2 |
| 17.9% (5/28) |
Class 4: No ortho substitution |
| 29% (29/100) |
