Fig. 4
Effect of various antibiotic concentrations on MN frequencies in TK6 cells. Cells were treated with negative or positive controls for 3 h in the absence (a–c) or presence (d–f) of S9 mix, followed by recovery culturing for 21 h using media supplemented with various concentrations of P/S (a and d), GM (b and e), or AP (c and f). MMC, 0.2 µg/mL; CP, 2.5 µg/mL;
, Mean of the historical positive control value;
, Lower limit of historical positive control range