Fig. 5

Histone acetylation by SCFAs and MMP-1 induction after treatment with CSS. (A) Structure of SCFAs. (B) MMP-1 induction and acetylation of histone H3 24 h after combined exposure to SCFAs and CSS. ASF-4-1 cells were treated with SCFAs (up to 10 mM), followed by treatment with CSS (2%). After incubation for 24 h, Western blotting was performed. Actin was used as a standard for the equal loading of proteins for SDS–PAGE